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This is the
$64,000 question. A review of the medical literature,
Vitamin C and Treatment of Cancer: Part I Abstracts and Commentary
from the Scientific Literature by Gary Null, Ph.D.; Howard Robins,
DPM; Mark Tanenbaum, DPM; and Patrick Jennings, Editor gives concise
conclusions for approximately 90 studies.
The most
famous work on this subject was by Pauling and Cameron. Dr. Cameron
was head of the Cancer department at Vale of Leven hospital. He and
Pauling decided to try giving 10 grams of Vitamin C a day to patients
that had exhausted conventional therapies. In this way, the patients
were not choosing between the Vitamin C and another treatment, nor was
the treatment combined with something else. The results of these
tests was published in Cameron and Pauling's book,
Cancer and Vitamin C.
Dr. Abram
Hoffer has been treating cancer patients with a nutritional program
for many years. The foundation of his nutritional protocol is vitamin
C. Below is a chart summerizing Hoffer's results treating over 1000
cancer with vitamin C (documented in the updated publishing of Cancer
and Vitamin C).
The point to
see in the chart above is the relative survival. For example, at the
end of 1994, about 70% (green line) of the 500+ (purple bar)
patients on Hoffer's nutritional plan were alive. In contrast, less
than 15% (blue line) of the 100+ patients not on the plan were alive
at years end. Please visit
Dr. Abram
Hoffer's page that relates his practice's experience treating
cancer patients.
There has
been some theory concerning vitamin C's potential role in protecting
not only healthy cells, but cancer cells as well, thereby interfering
with chemotherapy and radiation treatments. Hoffer's view on this is
(quoted from his website):
"This
[vitamin treatment] would enhance the therapeutic effect of the
chemotherapy and decrease its toxicity." Also, "If they
[cancer patients] needed chemotherapy the program [vitamin therapy]
would make it more tolerable and less painful and if they needed
radiation the program would decrease the intensity of the
side-effects of the radiation and increase its efficacy."
Also, a
recent article printed by InteliHealth from Johns Hopkins suggests
a positive impact on cancer from the antioxidant vitamins-C,E and Beta
Carotene. Also, please read the
article about the work of Sister Mary Eymard Poydock, Ph.D.,
director of cancer research and former professor of biology at
Mereyhurst College in Erie, Pennsylvania. An additional study on
vitamin C's possible role on prostate cancer
Effect of vitamin C on prostate cancer cells in vitro: effect on cell
number, viability, and DNA synthesis from Prostate, 1997 Aug,
32:3, 188-95 states (Background and Conclusions only):
BACKGROUND: Many studies describe the protective role of vitamin C
(ascorbic acid) against cancer development and in treatment of
established cancer. The present study investigated whether ascorbic
acid demonstrates a therapeutic benefit for prostate cancer.
CONCLUSIONS: Vitamin C inhibits cell division and growth through
production of hydrogen peroxide, which damages the cells probably
through an as yet unidentified free radical(s) generation/mechanism.
Our results also suggest that ascorbic acid is a potent anticancer
agent for prostate cancer cells.
Pauling's
stature in the scientific community meant that his work on Cancer
would not be ignored. Studies to replicate his work were done by the
Mayo Clinic, but not with much success. Pauling complained about the
procedures used-only post-chemotherapy patients were studied and
results included tracking of patients after C administration was
stopped!-to no avail. A second study was undertaken, but again, the
study procedure evoked complaints from Pauling. For a more thorough
explanation of these studies and additional reading about Pauling and
Cancer, please visit
Linus Pauling and Vitamin C Therapy at Health World. In any case,
given the situation presented the cancer patient, my opinion is to
take as much Vitamin C as possible regardless of other treatment
decisions. Pauling himself recommended surgery as an excellent option
where appropriate.
Work
involving cancer and Vitamin C points very strongly to the need to
take as much Vitamin C as your system is comfortable with. The
constant requirement for it and our inability for any long-term
storage (a stressful situation can deplete our supplies of C in
seconds!) means we all need to take C every single day. If you take
more C than your system can handle you will get the runs. This is
referred to as the "bowel tolerance limit" (please see
How Much to Take). If you are just starting to take C
supplementation, this level will be relatively low, but increase over
time. This is because certain enzyme systems will be enabled by the
increased C and this takes some time. It is interesting to note that
your limit will go up dramatically when you get sick. I normally take
about 14,000mg per day unless I feel like I'm coming down with
something (see
A Case of the Flu), then I've been able to take as much as
80,000mg in 24 hours. Cancer patients are advised to get intravenous
injections of C if possible, especially if they are having trouble
eating. Otherwise, I recommend taking C at least every hour to bowel
tolerance limit. If you have cancer, there is no good reason NOT to
try this, except the probable flack you will have to endure from the
medical community (please see the
strategy I discuss concerning surgery in the letters
section ). But it's your life and you have a right to try this,
especially since it can't hurt (be aware that building up your dosage
slowly is recommended - see
Cathcart's page on Titrating to bowel tolerance ).
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With the cooperation and
support of the Vitamin C Foundation, Cforyourself is
developing a project to demonstrate the therapeutic value of
vitamin C for cancer. Our approach will differ from other
studies that aim to produce results for the consumption of
the medical community. We will be attempting to present
results in a way that is captivating to the general public.
We need your support. We are looking for funding.
participating doctors and patients in the Baltimore, MD
area.
The following .pdf documents
outline our project:
Please
e-mail me with any questions or comments.
- Rusty Hoge
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Dr.
Klenner, who's work involved as much clinical experience as anyone in
the use of vitamin C felt that vitamin C may be extremely effective if
given in high enough doses. He explained in
his paper on C that an investigation should include intravenous C
at a rate of 100-300 grams per day! The Journal of Orthomolecular
Medicine has published an account worth reading of a patient's
experience with IV vitamin C entitled
Intravenous Vitamin C in a terminal Cancer Patient.
In the
words of Dr. Louis Lasagna (1981) of the University of Rochester
Medical School concerning vitamin C therapy for cancer patients,
"It seems indefensible not to at least try substantial doses of
vitamin C in these patients."
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Vitamin C plays an important role in our daily fight against cancer.
Due to its importance to the development of immune system cells, it is
crucial as a first line of defense against mutated cells from ever
multiplying into overt cancer. If cancer does get a foot-hold,
high-dose vitamin C still plays at least three important roles.
Immune System Enhancement
The first is as a raw material for the immune system. Even after the
most successful surgery, radiation- or chemo-therapy, some cancer
cells are bound to remain. It is our immune system that will hunt down
these cells and destroy them. Vitamin C is required for our immune
systems to generate and mobilize the specialized cells that fight
cancer and infections, too. The more stress your immune system is
under, the more vitamin C is used, if it is available. If it isn't
available, the disease will not be stopped.
Inhibition of Tumor Growth
Secondly, there is a cement, or ground substance, that holds our cells
together properly to form the integrity of our tissues. Dr. Ewan
Cameron theorized that cancer cells excrete a substance, hyaluronidase,
that breaks down the collagen and fibers that make up the structure of
this ground substance creating the space needed for tumor growth.
Vitamin C is required for the proper development of collagen and this
fibrous material. This is why vitamin C is so important to all tissue
related problems, including wound healing, spinal disc injuries, gum
problems and especially cardiovascular disease. Specifically in
cancer, proper tissue integrity will help encase a tumor and make it
much harder for it to grow.
Cytotoxic Properties
J.P. Casciari, N.H. Riordan, T.L. Schmidt, XL Meng, J.A. Jackson and
H.D. Riordan have demonstrated in the laboratory that vitamin C in
combination with other natural substances can actually be cytotoxic to
cancer cells. What this means is that these safe, non-toxic natural
substances can kill cancer cells in a way similar to chemotherapy.
These tests were done with concentrations of vitamin C that can be
duplicated in vivo. One of the authors and researchers of this paper
describing this function of vitamin C is Dr. Hugh Riordan. He is the
director of The Center for the Improvement of Human Functioning
International and one of the signatures of this project. This is the
organization we will be working with on our cancer project.
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